Details

Autor(en) / Beteiligte

• KNELLER, A
• RAANANI, P
• HARDAN, I
• AVIGDOR, A
• LEVI, I
• BERKOWICZ, M
• BEN-BASSAT, I

Titel

Therapy with thalidomide in refractory multiple myeloma patients — the revival of an old drug

Ist Teil von

• British journal of haematology, 2000-02, Vol.108 (2), p.391-393

Ort / Verlag

Oxford, U.K. and Cambridge, USA: Blackwell Science Ltd

Erscheinungsjahr

2000

Quelle

MEDLINE

Beschreibungen/Notizen

• We have treated 17 refractory or relapsed multiple myeloma patients resistant to chemotherapy with thalidomide at a dose of 200–800 mg/day. Eleven patients responded, five of whom had a very good partial response (> 75% decline in M protein) and another five exhibited a partial response (> 50% decline in M protein). Except for one patient, treatment was well tolerated with only mild side‐effects. Thalidomide should be included in the therapeutic options for refractory myeloma.