Details

Autor(en) / Beteiligte

• Sawka, Anna M., MD, PhD, FRCPC
• Brierley, James D., MBBS, FRCP, FRCR, FRCP(C)
• Tsang, Richard W., MD, FRCP(C)
• Thabane, Lehana, PhD
• Rotstein, Lorne, MD, FRCSC
• Gafni, Amiram, PhD
• Straus, Sharon, MD, MSc, FRCPC
• Goldstein, David P., MD, FRCSC

Titel

An Updated Systematic Review and Commentary Examining the Effectiveness of Radioactive Iodine Remnant Ablation in Well-Differentiated Thyroid Cancer

Ist Teil von

• Endocrinology and metabolism clinics of North America, 2008-06, Vol.37 (2), p.457-480

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2008

Quelle

MEDLINE

Beschreibungen/Notizen

• Radioactive iodine remnant ablation (RRA) is used to destroy residual normal thyroid tissue after complete gross surgical resection of papillary or follicular thyroid cancer. The article updates a prior systematic review of the literature to determine whether RRA decreases the risk of thyroid cancer-related death or recurrence at 10 years after initial surgery, including data from 28 studies. No long-term randomized trials were identified, so the review is limited to observational studies. The incremental benefit of RRA in low risk patients with well-differentiated thyroid cancer after total or near-total thyroidectomy who are receiving thyroid hormone suppressive therapy remains unclear.