Details

Autor(en) / Beteiligte

• Hadavi, Valeh
• Taromchi, Amir Hossein
• Malekpour, Mahdi
• Gholami, Behjat
• Law, Hai-Yang
• Almadani, Navid
• Afroozan, Fariba
• Sahebjam, Farhad
• Pajouh, Parisa
• Kariminejad, Roxana
• Kariminejad, Mohammad Hassan
• Azarkeivan, Azita
• Jafroodi, Maryam
• Tamaddoni, Ahmad
• Puehringer, Helene
• Oberkanins, Christian
• Najmabadi, Hossein

Titel

Elucidating the spectrum of alpha-thalassemia mutations in Iran

Ist Teil von

• Haematologica (Roma), 2007-07, Vol.92 (7), p.992-993

Ort / Verlag

Italy

Erscheinungsjahr

2007

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Alpha thalassemia (alpha-thal) is one of the most common hemoglobin (Hb) disorders in the world. Alpha-globin genes are located on chromosome 16. The majority of alpha-thal mutations are deletions but point mutations are found as well. Since the Iranian population is a mixture of different ethnic groups, frequency and distribution of alpha-globin mutations in various regions of the country need to be clarified. These findings can contribute to a wider understanding of this disorder.