Details

Autor(en) / Beteiligte

• Mathew, JS
• Saliki, JT
• Ewing, SA
• Lehenbauer, TW
• Panciera, RJ
• Malayer, , JR
• Cummings, CA
• Kocan, AA

Titel

An indirect enzyme-linked immunosorbent assay for diagnosis of American canine hepatozoonosis

Ist Teil von

• Journal of veterinary diagnostic investigation, 2001-01, Vol.13 (1), p.17-21

Ort / Verlag

Los Angeles, CA: J Vet Diagn Invest

Erscheinungsjahr

2001

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• College of Veterinary Medicine, Oklahoma State University, Stillwater 74078, USA. American canine hepatozoonosis (ACH), caused by Hepatozoon americanum, is an emerging tick-borne disease of dogs. An indirect enzyme-linked immunosorbent assay (ELISA) that should facilitate diagnosis of infection and study of the epidemiology of ACH has been developed using H. americanum sporozoites as antigen. Efficacy of the new test as a diagnostic tool was compared with that of skeletal muscle biopsy, the current gold standard for confirming H. americanum infection. Results show that the test is sensitive (93%) and specific (96%) and that it is as reliable as histopathologic examination of skeletal muscle for detecting infection. The ELISA would be suitable as a routine laboratory test for diagnosis of ACH.