Acta crystallographica. Section A, Foundations of crystallography, 2001-03, Vol.57 (2), p.163-175
2001
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Details
- Autor(en) / Beteiligte
- Titel
- An exponential modeling algorithm for protein structure completion by X-ray crystallography
- Ist Teil von
- Acta crystallographica. Section A, Foundations of crystallography, 2001-03, Vol.57 (2), p.163-175
- Ort / Verlag
- 5 Abbey Square, Chester, Cheshire CH1 2HU, England: Munksgaard International Publishers
- Erscheinungsjahr
- 2001
- Quelle
- Wiley Online Library - AutoHoldings Journals
- Beschreibungen/Notizen
- An exponential modeling algorithm is developed for protein structure completion by X‐ray crystallography and tested on experimental data from a 59‐residue protein. An initial noisy difference Fourier map of missing residues of up to half of the protein is transformed by the algorithm into one that allows easy identification of the continuous tube of electron density associated with that polypeptide chain. The method incorporates the paradigm of phase hypothesis generation and cross validation within an automated scheme.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0108-7673eISSN: 1600-5724DOI: 10.1107/S010876730001432XTitel-ID: cdi_proquest_miscellaneous_70649075
- Format
- –
- Schlagworte
- Algorithms, Analytical, structural and metabolic biochemistry, Biological and medical sciences, Condensed matter: structure, mechanical and thermal properties, Crystalline structure, Crystallography, X-Ray, Elapid Venoms - chemistry, Exact sciences and technology, Fourier Analysis, Fundamental and applied biological sciences. Psychology, General aspects, investigation methods, Models, Molecular, Molecular biophysics, Physics, protein, Protein Conformation, Proteins, Proteins - chemistry, Single-crystal and powder diffraction, Structure in molecular biology, Structure of solids and liquids, crystallography, X-ray diffraction and scattering