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Specific Bifidobacterium strains isolated from elderly subjects inhibit growth of Staphylococcus aureus
Ist Teil von
International journal of food microbiology, 2007-06, Vol.117 (1), p.125-128
Ort / Verlag
Amsterdam: Elsevier B.V
Erscheinungsjahr
2007
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
Cell-free, pH-controlled supernatants of thirty-eight
Bifidobacterium strains isolated from healthy elderly subjects were subjected to antimicrobial activity assay. Bioluminescent indicator strains
Staphylococcus aureus RN4220,
Escherichia coli K-12, and
Salmonella enterica serovar Typhimurium ATCC 14028 were used as targets of antimicrobial activity. The effect of nutrient depletion on the inhibition was eliminated with spent-culture controls. Three out of thirty-eight
Bifidobacterium strains were capable of inhibiting the growth of
S. aureus. The inhibition was equal to 23.2
±
19.1% to 50.4
±
26.7% of the inhibition caused by 50 IU/ml nisin. Reuterin-producing positive strain
Lactobacillus reuteri SD2112 was capable of 86.0
±
24.6% inhibition, but
Bifidobacterium lactis Bb-12, a known probiotic strain, showed no inhibition. None of the strains was capable of inhibiting the growth of
E. coli or
S. enterica. The observed inhibition by bifidobacteria was related to hydrogen peroxide formation and possible production of heat-stable proteinaceous compounds. The results suggest that production of antimicrobial substances other than organic acids is not common among
Bifidobacterium strains typical of elderly subjects. However, specific strains were identified which showed considerable inhibitory activity against
S. aureus.