Details

Autor(en) / Beteiligte

• Garcia, David A., MD
• Hylek, Elaine, MD, MPH

Titel

Reducing the Risk for Stroke in Patients Who Have Atrial Fibrillation

Ist Teil von

• Cardiology clinics, 2008-05, Vol.26 (2), p.267-275

Ort / Verlag

Netherlands: Elsevier Inc

Erscheinungsjahr

2008

Quelle

MEDLINE

Beschreibungen/Notizen

• Warfarin is highly effective at reducing the risk of stroke in AF. The benefit of oral anticoagulant therapy strongly outweighs the risk in most patients who have AF. More data are needed to define the overall risk-to-benefit ratio better for patients aged 80 years and older. Because a significant proportion of elderly individuals may not be optimal candidates for anticoagulant therapy, we must continue to evaluate alternative stroke prevention strategies while redoubling our efforts to understand the mechanisms underlying AF and thrombogenesis.