Details

Autor(en) / Beteiligte

• Moreno-Montañés, Javier, MD, PhD
• Alvarez, Aurora, DO
• Bes-Rastrollo, Maira, PhD
• García-Layana, Alfredo, MD, PhD

Titel

Optical coherence tomography evaluation of posterior capsule opacification related to intraocular lens design

Ist Teil von

• Journal of cataract and refractive surgery, 2008-04, Vol.34 (4), p.643-650

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

2008

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Purpose To evaluate posterior capsule opacification (PCO) and the impact of different intraocular lens (IOL) models on PCO characteristics using optical coherence tomography (OCT). Methods Eighty-three eyes with PCO (fibrosis or pearl type) and 32 pseudophakic eyes without PCO were included. Horizontal 3.0 mm long OCT scans of the posterior capsule were obtained. Measurements and means of the peak posterior capsule intensity (PCI) and posterior capsule thickness (PCT) (distance between 2 spikes at posterior capsule) at 3 scan points were recorded. The PCI and PCT were compared with best corrected visual acuity (BCVA) and IOL data. Results The PCT was high for IOLs with a rounded edge ( P = .001) and with poly(methyl methacrylate) (PMMA) IOLs ( P <.001). If the IOL optic was concave–convex, the PCT was higher than if the optic was biconvex ( P = .001). The PCT of hydrophilic acrylic IOLs was higher than of hydrophobic acrylic IOLs ( P = .04). Multivariate analysis of PCT showed that PMMA was the only factor statistically associated with PCT ( P = .02). The worse logMAR BCVA correlated significantly with a higher PCT value ( P <.001) but not with PCI ( P = .42). An IOL size of 12.5 mm was related to fibrosis-type PCO (odds ratio, 3.14; P = .04). Conclusions The PCT was most affected by IOL characteristics. Poly(methyl methacrylate) IOLs and IOLs with rounded edges were associated with higher PCT. Hydrophilic acrylic IOLs were associated with greater PCT than hydrophobic IOLs. Posterior capsule thickness was a factor in decreased BCVA.