The American journal of surgery, 2008-04, Vol.195 (4), p.427-432
2008
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- Autor(en) / Beteiligte
- Titel
- Differences in patient postoperative and long-term outcomes between obstructive and perforated colonic cancer
- Ist Teil von
- The American journal of surgery, 2008-04, Vol.195 (4), p.427-432
- Ort / Verlag
- New York, NY: Elsevier Inc
- Erscheinungsjahr
- 2008
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Abstract Background The aim of this observational study was to analyze the differences between patients with obstructive and perforated colonic cancer who managed with emergency curative surgery. Methods Between January 1994 and December 2000, patients deemed to have undergone curative resection for complicated colonic cancer were considered for inclusion in the study. They were classified into 2 groups: patients with obstructive cancer (OC) and patients with perforated cancer (PC). The main end points were postsurgical outcomes and long-term overall survival, cancer-related survival, and tumor recurrence. Results Of the 236 patients, surgery was deemed to be radical and performed with intent to cure in 155 patients (65.7%): 117 patients in the OC group and 38 patients in the PC group. No statistical differences were observed between the percentage of radical surgery between the 2 groups ( P = .63). The overall postsurgical mortality rate was 12.2%: 14 patients in the OC group and 5 patients in the PC group ( P = .839). Overall survival, probability of being free of recurrence, and cancer-related survival of the entire series were 64.57%, 67.72% and 73.03%, respectively. There were no differences between the 2 groups with respect to tumor recurrence, type of recurrence, overall survival, probability of being free of recurrence, and cancer-related survival at 5 years. Conclusions In our experience, patients with perforated colonic cancer do not seem to show worse long-term outcomes than those with OC. Studies with larger series are needed for further investigations.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0002-9610eISSN: 1879-1883DOI: 10.1016/j.amjsurg.2007.02.027Titel-ID: cdi_proquest_miscellaneous_70423729
- Format
- –
- Schlagworte
- Adult, Aged, Aged, 80 and over, Biological and medical sciences, Colectomy - methods, Colectomy - mortality, Colonic Neoplasms - complications, Colonic Neoplasms - mortality, Colonic Neoplasms - pathology, Colonic Neoplasms - surgery, Colorectal cancer, Disease-Free Survival, Emergency surgery, Emergency Treatment, Female, Gastroenterology. Liver. Pancreas. Abdomen, General aspects, Humans, Intestinal Obstruction - etiology, Intestinal Obstruction - mortality, Intestinal Obstruction - surgery, Intestinal Perforation - etiology, Intestinal Perforation - mortality, Intestinal Perforation - surgery, Lymph Node Excision, Lymphatic Metastasis, Male, Medical sciences, Medical treatment, Middle Aged, Mortality, Neoplasm Invasiveness, Neoplasm Recurrence, Local - prevention & control, Neoplasm Staging, Obstructive colonic cancer, Older people, Perforated colonic cancer, Recurrence, Stomach. Duodenum. Small intestine. Colon. Rectum. Anus, Surgery, Survival, Survival Analysis, Treatment Outcome, Tumors