Details

Autor(en) / Beteiligte

• Das, Sai Krupa
• Gilhooly, Cheryl H
• Golden, Julie K
• Pittas, Anastassios G
• Fuss, Paul J
• Cheatham, Rachel A
• Tyler, Stephanie
• Tsay, Michelle
• McCrory, Megan A
• Lichtenstein, Alice H
• Dallal, Gerard E
• Dutta, Chhanda
• Bhapkar, Manjushri V
• DeLany, James P
• Saltzman, Edward
• Roberts, Susan B

Titel

Long-term effects of 2 energy-restricted diets differing in glycemic load on dietary adherence, body composition, and metabolism in CALERIE: a 1-y randomized controlled trial

Ist Teil von

• The American journal of clinical nutrition, 2007-04, Vol.85 (4), p.1023-1030

Ort / Verlag

Bethesda, MD: American Society for Nutrition

Erscheinungsjahr

2007

Link zum Volltext

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• BACKGROUND:There remains no consensus about the optimal dietary composition for sustained weight loss. OBJECTIVE:The objective was to examine the effects of 2 dietary macronutrient patterns with different glycemic loads on adherence to a prescribed regimen of calorie restriction (CR), weight and fat loss, and related variables. DESIGN:A randomized controlled trial (RCT) of diets with a high glycemic load (HG) or a low glycemic load (LG) at 30% CR was conducted in 34 healthy overweight adults with a mean (±SD) age of 35 ± 6 y and body mass index (kg/m²) of 27.6 ± 1.4. All food was provided for 6 mo in diets controlled for confounding variables, and subjects self-administered the plans for 6 additional months. Primary and secondary outcomes included energy intake measured by doubly labeled water, body weight and fatness, hunger, satiety, and resting metabolic rate. RESULTS:All groups consumed significantly less energy during CR than at baseline (P < 0.01), but changes in energy intake, body weight, body fat, and resting metabolic rate did not differ significantly between groups. Both groups ate more energy than provided (eg, 21% and 28% CR at 3 mo and 16% and 17% CR at 6 mo with HG and LG, respectively). Percentage weight change at 12 mo was -8.04 ± 4.1% in the HG group and -7.81 ± 5.0% in the LG group. There was no effect of dietary composition on changes in hunger, satiety, or satisfaction with the amount and type of provided food during CR. CONCLUSIONS:These findings provide more detailed evidence to suggest that diets differing substantially in glycemic load induce comparable long-term weight loss.