Biotechnology and bioengineering, 2008-03, Vol.99 (4), p.1028-1033
2008
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- Autor(en) / Beteiligte
- Titel
- Enzymatic enantioselective C-C-bond formation in microreactors
- Ist Teil von
- Biotechnology and bioengineering, 2008-03, Vol.99 (4), p.1028-1033
- Ort / Verlag
- Hoboken: Wiley Subscription Services, Inc., A Wiley Company
- Erscheinungsjahr
- 2008
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- We have demonstrated that multiple crude enzyme lysates containing a hydroxynitrile lyase can be used for the enantioselective synthesis of cyanohydrins from aldehydes in microchannels. Using a microreactor setup, two important parameters were efficiently screened consuming only minute amounts of reagents. More importantly, results from the continuous flow reaction were fully consistent with results obtained from larger batchwise processes in which a stable emulsion was formed. Biotechnol. Bioeng. 2008; 99; 1028-1033. © 2007 Wiley Periodicals, Inc.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0006-3592eISSN: 1097-0290DOI: 10.1002/bit.21649Titel-ID: cdi_proquest_miscellaneous_70256408
- Format
- –
- Schlagworte
- Aldehydes - chemistry, Bioconversions. Hemisynthesis, Biological and medical sciences, Bioreactors, Biotechnology, Carbon - chemistry, Carbon-Carbon Lyases - chemistry, Catalysis, Chemical reactions, crude lysates, enzyme catalysis, Enzymes, Flow Injection Analysis - methods, Fundamental and applied biological sciences. Psychology, Hevea - enzymology, lyases, Medical screening, Methods. Procedures. Technologies, Microfluidic Analytical Techniques - methods, microreactors, Nitriles - chemistry, screening