Details

Autor(en) / Beteiligte

• KIM, N.
• LEE, S. W.
• CHO, S. I.
• PARK, C. G.
• YANG, C. H.
• KIM, H. S.
• REW, J. S.
• MOON, J. S.
• KIM, S.
• PARK, S. H.
• JUNG, H. C.
• CHUNG, I. S.

Titel

The prevalence of and risk factors for erosive oesophagitis and non‐erosive reflux disease: a nationwide multicentre prospective study in Korea

Ist Teil von

• Alimentary pharmacology & therapeutics, 2008-01, Vol.27 (2), p.173-185

Ort / Verlag

Oxford, UK: Blackwell Publishing Ltd

Erscheinungsjahr

2008

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Summary Background  Prospective nationwide multicentre studies that have evaluated endoscopic findings and reflux symptoms using a well‐designed questionnaire are very rare. Aim  To compare the prevalence rates of and risk factors for erosive oesophagitis and non‐erosive reflux disease (NERD) in the Korean population. Methods  A gastroscopic examination was performed on 25 536 subjects who visited 40 Healthcare Centers for a health check‐up. A gastro‐oesophageal reflux questionnaire and multivariate analysis were used to determine the risk factors for erosive oesophagitis and NERD. Results  2019 (8%) and 996 subjects (4%) had erosive oesophagitis and non‐erosive reflux disease, respectively; only 58% of subjects with erosive oesophagitis had reflux symptoms. Multivariate analysis showed that the risk factors for erosive oesophagitis and NERD differed, i.e. those of erosive oesophagitis were male, a Helicobacter pylori eradication history, alcohol, body mass index ≥25 and hiatal hernia. In contrast, the risk factors for NERD were female, age <40 and ≥60 vs. 40–59 years, body mass index <23 and a monthly income <$1000, glucose ≥126 mg/dL, smoking, a stooping posture at work and antibiotic usage. Conclusions  The prevalence rates of erosive oesophagitis and NERD were 8% and 4%, respectively, in Korean health check‐up subjects. The risk factors for erosive oesophagitis and NERD were found to differ, which indicates that their underlying pathogeneses are distinct.