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The aim of the prospective two-armed open study was to examine the effect of
Lycopi europaei herba on thyroid function and on associated symptoms during a 3-month follow-up phase. The study population consisted of patients with a basal TSH<1.0
mU/l and hyperthyroidism-associated symptoms.
For the first time, the T
3/T
4 excretion in 24
h urine was measured as a primary objective parameter. As secondary parameters, further hormones, the general condition and the symptoms associated with hyperthyroidism were registered.
The urinary T
4 excretion was significantly increased in
Lycopus europaeus-treated patients (
p=0.032). It is supposed that renal mechanisms cause the increased T
4 excretion either by a modification within the glomeruli or by impaired reabsorption.
Symptoms being specific to the thyroid gland were diminished, as e.g. the increased heart rate in the morning. The
Lycopus europaeus preparation showed a good tolerance.
These findings confirm positive effects of
Lycopus europaeus in slight forms of hyperthyroidism.