Details

Autor(en) / Beteiligte

• Huisman, E M
• van Dillen, T
• Onck, P R
• Van der Giessen, E

Titel

Three-dimensional cross-linked F-actin networks: relation between network architecture and mechanical behavior

Ist Teil von

• Physical review letters, 2007-11, Vol.99 (20), p.208103-208103, Article 208103

Ort / Verlag

United States

Erscheinungsjahr

2007

Quelle

PROLA - Physical Review Online Archive

Beschreibungen/Notizen

• Numerical simulations are reported for the response of three-dimensional cross-linked F-actin networks when subjected to large deformations. In addition to the physiological parameters such as actin and cross-linker concentration, the model explicitly accounts for filament properties and network architecture. Complementary to two-dimensional studies, we find that the strain-stiffening characteristics depend on network architecture through the local topology around cross-links.