Nucleosides & nucleotides, 1999-04, Vol.18 (4-5), p.1005-1006
1999
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Details
- Autor(en) / Beteiligte
- Titel
- Comparison of anti-HBV activity of beta-D- and beta-L-DDA-5'monophosphate prodrugs and effectiveness in combination with lamivudine
- Ist Teil von
- Nucleosides & nucleotides, 1999-04, Vol.18 (4-5), p.1005-1006
- Ort / Verlag
- United States
- Erscheinungsjahr
- 1999
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- We have investigated the effects of several beta-D-ddA 5'-monophospate (beta-D-ddAMP), and their corresponding beta-L-enantiomers prodrugs against HBV replication. All ddAMP prodrugs inhibited HBV replication in a dose-dependent manner.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0732-8311Titel-ID: cdi_proquest_miscellaneous_69936037
- Format
- –
- Schlagworte
- AIDS/HIV, Antiviral Agents - pharmacology, Cell Line, Deoxyadenine Nucleotides - pharmacology, Dideoxynucleotides, Hepatitis B virus - drug effects, Hepatitis B virus - physiology, Lamivudine - pharmacology, Microbial Sensitivity Tests, Stereoisomerism, Virus Replication - drug effects