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The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994
Ist Teil von
The New England journal of medicine, 1999-08, Vol.341 (8), p.556-562
Ort / Verlag
Boston, MA: Massachusetts Medical Society
Erscheinungsjahr
1999
Quelle
MEDLINE
Beschreibungen/Notizen
Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease in the United States. Before the characterization of HCV,
1
,
2
the magnitude of infection could not be reliably determined because assessment of clinical disease (i.e., non-A, non-B hepatitis) underestimated the true extent of infection. After tests to detect antibody to HCV (anti-HCV) became available, studies to determine the prevalence of HCV infection in the general population were performed, mostly with volunteer blood donors as the subjects.
3
,
4
However, the prevalence of HCV among blood donors does not reflect the prevalence in the general population, since even first-time . . .