Details

Autor(en) / Beteiligte

• Prades, Amparo
• Corberán, Rosa
• Poyatos, Macarena
• Peris, Eduardo

Titel

[IrCl2Cp(NHC)] Complexes as Highly Versatile Efficient Catalysts for the Cross-Coupling of Alcohols and Amines

Ist Teil von

• Chemistry : a European journal, 2008-12, Vol.14 (36), p.11474-11479

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2008

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• A comparative study on the catalytic activity of a series of [IrCl2Cp*(NHC)] complexes in several C–O and C–N coupling processes implying hydrogen‐borrowing mechanisms has been performed. The compound [IrCl2Cp*(InBu)] (Cp*=pentamethyl cyclopentadiene; InBu=1,3‐di‐n‐butylimidazolylidene) showed to be highly effective in the cross‐coupling reactions of amines and alcohols, providing high yields in the production of unsymmetrical ethers and N‐alkylated amines. A remarkable feature is that the processes were carried out in the absence of base, phosphine, or any other external additive. A comparative study with other known catalysts, such as Shvo's catalyst, is also reported. Multifunctional catalyst: The compound [IrCl2Cp*(InBu)] has been used in the cross‐coupling reactions of amines and alcohols, providing high yields in the production of unsymmetrical ethers and N‐alkylated aromatic amines (see scheme).