Details

Autor(en) / Beteiligte

• Cerutti, A

Titel

Location, location, location: B-cell differentiation in the gut lamina propria

Ist Teil von

• Mucosal immunology, 2008-01, Vol.1 (1), p.8-10

Ort / Verlag

United States: Nature Publishing Group

Erscheinungsjahr

2008

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The intestinal immune system includes an immunoglobulin (Ig)A-inductive site represented by Peyer's patches (PPs) and an IgA effector site represented by the lamina propria (LP). This canonical map of intestinal IgA production has been blurred recently by studies showing the presence of active IgA class switching in the LP. Here we discuss the functional implications and controversial nature of these findings.