Details

Autor(en) / Beteiligte

• Avetta, Christopher T
• Konkol, Leah C
• Taylor, Carla N
• Dugan, Karen C
• Stern, Charlotte L
• Thomson, Regan J

Titel

Diastereoselective Oxidative Carbon−Carbon Bond Formation via Silyl Bis-enol Ethers

Ist Teil von

• Organic letters, 2008-12, Vol.10 (24), p.5621-5624

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2008

Quelle

MEDLINE

Beschreibungen/Notizen

• Diisopropylsilyl bis-enol ethers are shown to be powerful intermediates for the diastereoselective dimerization and cross-coupling of cyclic ketones. The trends observed for the oxidative coupling of a range of different dialkylsilyl bis-enol ethers derived from cyclohexanone are rationalized by invoking a stereochemical model based on a Thorpe−Ingold effect.