Details

Autor(en) / Beteiligte

• Pediatric Eye Disease Investigator Group

Titel

A Randomized Trial of Near Versus Distance Activities While Patching for Amblyopia in Children Aged 3 to Less Than 7 Years

Ist Teil von

• Ophthalmology (Rochester, Minn.), 2008-11, Vol.115 (11), p.2071-2078.e5

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

2008

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Purpose To determine whether performing near activities while patching for amblyopia enhances improvement in visual acuity. Design Randomized clinical trial. Participants A total of 425 children, aged 3 to <7 years, with amblyopia (20/40–20/400) that was caused by anisometropia, strabismus, or both, and that persisted after treatment with spectacles. Methods Children were randomized to 2 hours of patching per day with near activities or 2 hours of patching per day with distance activities. Instruction sheets describing common near and distance activities were given to the parents. Study visits were scheduled at 2, 5, 8, and 17 weeks. In weeks without a visit, weekly telephone calls were made to the parent to monitor and encourage compliance during the first 8 weeks. Main Outcome Measure Masked assessment of visual acuity by isolated crowded HOTV optotypes at 8 weeks. Results At 8 weeks, improvement in amblyopic eye visual acuity averaged 2.6 lines in the distance activities group and 2.5 lines in the near activities group (mean difference in acuity between groups, adjusted for baseline acuity, 0.0 lines 95% confidence interval, −0.3 to 0.3). The 2 groups also appeared statistically similar at the 2-, 5-, and 17-week visits. At the 17-week examination, children with severe amblyopia improved a mean of 3.6 lines with 2 hours of daily patching. Conclusions Performing common near activities does not improve visual acuity outcome when treating anisometropic, strabismic, or combined amblyopia with 2 hours of daily patching. Children with severe amblyopia may respond to 2 hours of daily patching. Financial Disclosure(s) The authors have no proprietary or commercial interest in any materials discussed in this article.