Details

Autor(en) / Beteiligte

• Cao, Shou-gen
• Zhou, Yan-bing
• Zhang, Cai-kun
• Chen, Dong
• Yu, Yun-yun
• Lu, Lian-fang

Titel

Effect of intensive insulin therapy on the clinical results of postoperative patients with gastric cancer

Ist Teil von

• Chung-hua wai kʿo tsa chih, 2008-06, Vol.46 (12), p.918-920

Ort / Verlag

China

Erscheinungsjahr

2008

Quelle

MEDLINE

Beschreibungen/Notizen

• To investigate the influence of intensive insulin therapy on the results of postoperative patients with gastric cancer. Forty-six patients with gastric cancer underwent radical operation were randomly divided into two groups: intensive group (n=23, to control blood glucose at 4.4 to 6.1 mmol/L) and conventional group (n=23, to control blood glucose at 10.0 to 11.1 mmol/L). Fasting blood glucose( FBG), fasting insulin (FINS), tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) and C reaction protein (CRP) in 46 patients were detected dynamically during perioperative period. Insulin resistance index (HOMA-IR) were calculated using Homeostasis Model Assessment (HOMA) to evaluate insulin sensitivity. Postoperative complications and other clinical data were recorded. No hypoglycemia occurred in the two groups. Compared with conventional group, morbidity and postoperative duration of fever, antibiotic use and the length of hospital stay in intensive group were significantly reduced (P < 0.05). On the day