Trends in Biochemical Sciences, 1999-05, Vol.24 (5), p.199-202
1999
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- Autor(en) / Beteiligte
- Titel
- Degrading chloroplast mRNA: the role of polyadenylation
- Ist Teil von
- Trends in Biochemical Sciences, 1999-05, Vol.24 (5), p.199-202
- Ort / Verlag
- England: Elsevier Ltd
- Erscheinungsjahr
- 1999
- Quelle
- Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
- Beschreibungen/Notizen
- Chloroplast development involves changes in the stability of specific plastid mRNAs. To understand how the half-lives of these mRNAs are modified, several laboratories are investigating how plastid mRNAs are degraded. This has led to the isolation of a high-molecular-weight complex that contains an endoribonuclease and a 3′–5′ exoribonuclease, and the discovery that efficient mRNA degradation requires polyadenylation. These findings are similar to recent discoveries in Escherichia coli. However, an important difference between the two systems is that chloroplast mRNA degradation involves nuclear-encoded proteins. Modification of these proteins could provide the mechanism for altering plastid-mRNA half-lives in response to developmental stimuli.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0968-0004eISSN: 1362-4326DOI: 10.1016/S0968-0004(99)01388-2Titel-ID: cdi_proquest_miscellaneous_69753750
- Format
- –
- Schlagworte
- 28RNP, Chloroplast mRNA, Chloroplasts - genetics, Escherichia coli, Models, Biological, mRNA degradation, mRNA stability, Nuclear Proteins - metabolism, Plastids - genetics, Poly A, Polyadenylation, Regulatory Sequences, Nucleic Acid, ribonuclease, RNA, Bacterial - metabolism, RNA, Messenger - metabolism