Details

Autor(en) / Beteiligte

• Ellis, R John
• Hartl, F Ulrich

Titel

Principles of protein folding in the cellular environment

Ist Teil von

• Current opinion in structural biology, 1999-02, Vol.9 (1), p.102-110

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

1999

Quelle

Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)

Beschreibungen/Notizen

• The ability of newly synthesised protein chains to fold into their functional conformations has evolved within the complex intracellular environment. Until recently, however, this ability has been studied largely as the refolding of denatured mature proteins in dilute simple solutions. Recent work aimed at understanding how proteins fold in vivo has allowed some general statements to be postulated.