Details

Autor(en) / Beteiligte

• SCHULTZE, J. L
• DONOVAN, J. W
• GRIBBEN, J. G

Titel

Minimal residual disease detection after myeloablative chemotherapy in chronic lymphatic leukemia

Ist Teil von

• Journal of molecular medicine (Berlin, Germany), 1999-02, Vol.77 (2), p.259-265

Ort / Verlag

Berlin: Springer

Erscheinungsjahr

1999

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Detection of clonal tumor cells in leukemias and lymphomas by PCR in minimal residual disease (MRD) has been shown to be a valuable parameter for identifying patients who may require further treatment. Here we introduce the studies underway in our own and other institutions addressing the value of PCR technology in detecting residual CLL cells either in the autologous stem cell product or after induction of MRD in patients after autologous or allogeneic stem cell transplant. The PCR technology used for these questions and the results are discussed.