Trends in parasitology, 2008-09, Vol.24 (9), p.379-382
2008
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- Autor(en) / Beteiligte
- Titel
- Will new antischistosomal drugs finally emerge?
- Ist Teil von
- Trends in parasitology, 2008-09, Vol.24 (9), p.379-382
- Ort / Verlag
- Oxford: Elsevier Ltd
- Erscheinungsjahr
- 2008
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- It has been often observed that the chemotherapeutic armamentarium against an important disease such as schistosomiasis consists of just one drug, praziquantel. Thus, development of drug resistance is an impending danger, with serious implications for the health protection of many millions of people. This rational and legitimate concern might now begin to be relieved by the recent proposal of a new class of compounds that could represent a novel source of drugs against schistosomiasis.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1471-4922eISSN: 1471-5007DOI: 10.1016/j.pt.2008.05.006Titel-ID: cdi_proquest_miscellaneous_69464433
- Format
- –
- Schlagworte
- Animals, Antibiotics. Antiinfectious agents. Antiparasitic agents, Antiparasitic agents, Biological and medical sciences, Combinatorial Chemistry Techniques, Drug Approval, Drug Design, Drug Resistance, Gastroenterology and Hepatology, Glutathione, Humans, Infectious Disease, Medical sciences, Multienzyme Complexes - antagonists & inhibitors, Multienzyme Complexes - metabolism, NADH, NADPH Oxidoreductases - antagonists & inhibitors, NADH, NADPH Oxidoreductases - metabolism, Oxidation-Reduction, Pharmacology. Drug treatments, Schistosoma, Schistosoma - drug effects, Schistosoma - metabolism, Schistosomiasis - drug therapy, Schistosomicides - chemistry, Schistosomicides - classification, Schistosomicides - pharmacology, Thioredoxins