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Assessment and Significance of Left Ventricular Mass by Cardiovascular Magnetic Resonance in Hypertrophic Cardiomyopathy
Ist Teil von
Journal of the American College of Cardiology, 2008-08, Vol.52 (7), p.559-566
Ort / Verlag
United States: Elsevier Inc
Erscheinungsjahr
2008
Quelle
ScienceDirect
Beschreibungen/Notizen
Assessment and Significance of Left Ventricular Mass by Cardiovascular Magnetic Resonance in Hypertrophic Cardiomyopathy Iacopo Olivotto, Martin S. Maron, Camillo Autore, John R. Lesser, Luigi Rega, Giancarlo Casolo, Marcello De Santis, Giovanni Quarta, Stefano Nistri, Franco Cecchi, Carol J. Salton, James E. Udelson, Warren J. Manning, Barry J. Maron, Left ventricular (LV) mass was assessed by cardiovascular magnetic resonance in 264 patients with hypertrophic cardiomyopathy (HCM), and compared with LV mass in 606 healthy control subjects. The LV mass index in HCM patients significantly exceeded that of control subjects, but was within normal range in 56 patients (21%), and only mildly increased in 18 (16%). Left ventricular mass was weakly related to maximal LV thickness (r2 = 0.38; p < 0.001). During follow-up, markedly increased LV mass index proved a more sensitive predictor of outcome than extreme maximal wall thickness. In distinction to prior perceptions, increased LV mass is not required to establish the clinical diagnosis of HCM.