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Characterization of a Highly Cross-linked Ultrahigh Molecular-Weight Polyethylene in Clinical Use in Total Hip Arthroplasty
Ist Teil von
The Journal of arthroplasty, 2008-08, Vol.23 (5), p.751-761
Ort / Verlag
United States: Elsevier Inc
Erscheinungsjahr
2008
Quelle
MEDLINE
Beschreibungen/Notizen
Abstract This article reports on a commercially available extensively cross-linked ultrahigh molecular-weight polyethylene (HXPE) produced by subjecting molded GUR 1050 ultrahigh molecular-weight polyethylene (UHMWPE) to 100 ± 10 kGy of electron beam radiation followed by melt annealing and sterilization by gas plasma. When compared to contemporary conventional molded GUR 1050 UHMWPE sterilized by 37 kGy of gamma radiation, the HXPE material has enhanced wear properties, has no detectable free radicals, and is resistant to oxidation and oxidative-related material property changes. The relative wear improvement of the HXPE is maintained in the presence of bone cement or alumina particles. The HXPE produced greater than 90% fewer wear particles in all size ranges and statistically significantly ( P < .0001) smaller average-size particles than did the conventional UHMWPE.