Details

Autor(en) / Beteiligte

• Daum, Douglas R
• Smith, Nadine B
• King, Randy
• Hynynen, Kullervo

Titel

In vivo demonstration of noninvasive thermal surgery of the liver and kidney using an ultrasonic phased array

Ist Teil von

• Ultrasound in medicine & biology, 1999-09, Vol.25 (7), p.1087-1098

Ort / Verlag

Amsterdam: Elsevier Inc

Erscheinungsjahr

1999

Quelle

Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)

Beschreibungen/Notizen

• A 256-element, continuous-wave ultrasonic phased array has been used to thermally coagulate deep-seated liver and kidney tissue. The array elements were formed on a 1–3 piezocomposite bowl with a 10-cm radius of curvature and 12-cm diameter. The 0.65 × 0.65 cm 2 projection elements were driven at 1.1 MHz by a custom-built amplifier system. A series of in vivo porcine experiments demonstrated the ability to coagulate liver and kidney tissue using the large-scale phased array. The temperature response of the treatment was guided and monitored using magnetic resonance (MR) images. Focal lesion volumes greater than 0.5 cm 3 in kidney and 2 cm 3 in liver were formed from a single 20-s sonication.