Details

Autor(en) / Beteiligte

• Ajith Kumar, Vadakke Kanakath
• Gold, June Anne
• Mallon, Eleanor
• Thomas, Shyamala
• Hodgson, Shirley V.

Titel

Sebaceous adenomas in an MYH associated polyposis patient of Indian (Gujarati) origin

Ist Teil von

• Familial cancer, 2008-06, Vol.7 (2), p.187-189

Ort / Verlag

Dordrecht: Springer Netherlands

Erscheinungsjahr

2008

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• MYH associated polyposis is an autosomal recessive polyposis syndrome with a high risk of large bowel cancer, caused by mutations in the DNA repair gene MYH. Founder mutations have been described in different ethnic groups. Muir Torre Syndrome is the association of internal malignancies with sebaceous gland tumours; Lynch Syndrome/Hereditary Non Polyposis Cancer is the best known cause. There has been a previous report of sebaceous gland tumours in an Italian patient with MYH associated polyposis. We describe a man of Indian (Gujarati) descent who has MYH associated polyposis and multiple sebaceous adenomas of the skin.