Details

Autor(en) / Beteiligte

• Héry, C.
• Ferlay, J.
• Boniol, M.
• Autier, P.

Titel

Changes in breast cancer incidence and mortality in middle-aged and elderly women in 28 countries with Caucasian majority populations

Ist Teil von

• Annals of oncology, 2008-05, Vol.19 (5), p.1009-1018

Ort / Verlag

Oxford: Oxford University Press

Erscheinungsjahr

2008

Quelle

MEDLINE

Beschreibungen/Notizen

• Background: Mammography screening and menopause hormone therapy is essentially offered to women 50–69 years old. Methods: In 28 European ancestry countries, we quantified changes in breast cancer incidence and mortality using a joinpoint regression analysis from 1960 until last year of available data. Results: Since 1960, increases in incidence often in the order of 2%–3% per year occurred in all countries, mainly in women 50–69 years old whose incidence in eight countries surpassed the incidence in women 70 years old and more. In 10 countries, a decrease in incidence in women ≥70 years was noticeable in the last years of observation, but the magnitude of this decrease was far from matching the magnitude of the increases observed in the 50–69 age-group. In the beginning of years 2000s, a persistent decrease in mortality of ∼2% per year was observed in women 50–69 years old in most countries and parallel declines in mortality were observed in women 70 years or more. Conclusions: In years 2000s, in a number of countries, the incidence of breast cancer has become greater in middle-aged women than in older women. If trends remain unchanged, the same phenomenon is likely to happen in other countries.