Details

Autor(en) / Beteiligte

• Holmes, Gregory L.
• Ben-Ari, Yehezkel

Titel

Seizures in the Developing Brain: Perhaps Not So Benign after All

Ist Teil von

• Neuron, 1998-12, Vol.21 (6), p.1231-1234

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

1998

Quelle

MEDLINE

Beschreibungen/Notizen

• Seizures are one of the most common yet frightening neurological conditions encountered in humans. While seizures can occur at any age, affecting at least 2% of the population at one point or another, they are far more common in children than adults. The highest incidence of seizures occurs during the first year of life. While some infants with neonatal seizures fare well, in many cases the seizures are a sign of an ominous neurological disorder. There are many unanswered questions regarding neonatal seizures. What are the features of the immature brain that make it so prone to seizures? What are the consequences of seizures during early brain development? Because of the ethical and logistical difficulties in performing studies in ill newborns, much of our insight into the pathophysiology and consequences of neonatal seizures have necessarily come from animal studies.