Details

Autor(en) / Beteiligte

• Takao, Sonshin
• Aikou, Takashi
• Shinchi, Hiroyuki
• Uchikura, Keiichirou
• Kubo, Masaaki
• Imamura, Hiroshi
• Maenohara, Shigeho

Titel

Comparison of relapse and long-term survival between pylorus-preserving and whipple pancreaticoduodenectomy in periampullary cancer

Ist Teil von

• The American journal of surgery, 1998-11, Vol.176 (5), p.467-470

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

1998

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Background: Whether long-term survival and type of recurrence in periampullary cancer are influenced by the type of surgical procedure or not is still obscure. The purpose of this review was to analyze the results at a single institution. Methods: Between 1982 and 1996, 113 consecutive patients with either distal bile duct or ampullary cancers underwent either pylorus-preserving pancreaticoduodenectomy (PPPD) or the Whipple procedure. The median follow-up was 30 months (range 12 to 150). Patient records were reviewed to determine type of recurrence and survival. Results: In distal bile duct or ampullary cancers, comparison of actuarial survival curves between PPPD and the Whipple operation revealed no significant differences. Even in node-positive patients, the 5-year survival rates did not differ significantly between those undergoing PPPD or the Whipple operation. Tumor recurrence was not correlated with the operative method, although among types of tumor recurrence, the rate of blood-borne metastasis was higher in distal bile duct or ampullary cancers. Conclusions: PPPD is an acceptable alternative to the Whipple procedure in the treatment of periampullary cancer. Long-term survival and type of recurrence were not influenced by these types of surgical procedures.