Details

Autor(en) / Beteiligte

• LORING, DAVID W.
• STRAUSS, ESTHER
• HERMANN, BRUCE P.
• BARR, WILLIAM B.
• PERRINE, KENNETH
• TRENERRY, MAX R.
• CHELUNE, GORDON
• WESTERVELD, MICHAEL
• LEE, GREGORY P.
• MEADOR, KIMFORD J.
• BOWDEN, STEPHEN C.

Titel

Differential neuropsychological test sensitivity to left temporal lobe epilepsy

Ist Teil von

• Journal of the International Neuropsychological Society, 2008-05, Vol.14 (3), p.394-400

Ort / Verlag

New York, USA: Cambridge University Press

Erscheinungsjahr

2008

Quelle

MEDLINE

Beschreibungen/Notizen

• We examined the sensitivity of the Rey Auditory Verbal Learning Test (AVLT), California Verbal Learning Test (CVLT), Boston Naming Test (BNT), and Multilingual Aphasia Examination Visual Naming subtest (MAE VN) to lateralized temporal lobe epilepsy (TLE) in patients who subsequently underwent anterior temporal lobectomy. For the AVLT (n = 189), left TLE patients performed more poorly than their right TLE counterparts [left TLE = 42.9 (10.6), right TLE = 47.7 (9.9); p < .002 (Cohen's d = .47)]. Although statistically significant, the CVLT group difference (n = 212) was of a smaller magnitude [left LTE = 40.7 (11.1), right TLE = 43.8 (9.9); (p < .03, Cohen's d = .29)] than the AVLT. Group differences were also present for both measures of confrontation naming ability [BNT: left LTE = 43.1 (8.9), right TLE = 48.1 (8.9); p < .001 (Cohen's d = .56); MAE VN: left TLE = 42.2, right TLE = 45.6, p = .02 (Cohen's d = .36)]. When these data were modeled in independent logistic regression analyses, the AVLT and BNT both significantly predicted side of seizure focus, although the positive likelihood ratios were modest. In the subset of 108 patients receiving both BNT and AVLT, the AVLT was the only significant predictor of seizure laterality, suggesting individual patient variability regarding whether naming or memory testing may be more sensitive to lateralized TLE. (JINS, 2008, 14, 394–400.)