Details

Autor(en) / Beteiligte

• Reuther, M
• Spottke, E.A
• Klotsche, J
• Riedel, O
• Peter, H
• Berger, K
• Athen, O
• Köhne-Volland, R
• Dodel, R.C

Titel

Assessing health-related quality of life in patients with Parkinson's disease in a prospective longitudinal study

Ist Teil von

• Parkinsonism & related disorders, 2007-03, Vol.13 (2), p.108-114

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2007

Quelle

MEDLINE

Beschreibungen/Notizen

• Abstract Objective To prospectively assess the health-related quality of life (HrQoL) in Parkinson's disease (PD) during 12 months. Methods HrQoL was assessed in 145 PD patients using the PD-specific PDQ-39, PDQL and the generic EQ-5D. In addition, clinical rating-scales were used. Results All scales showed a pronounced effect of PD. In comparison to an age-matched population the EQ-5D was considerably affected. In comparison to baseline, however, there was no significant change in the generic scale but a significant change in the sum-score of disease-specific HrQoL-scales. Conclusions Only disease-specific scales were sensitive to change. Further studies are necessary to evaluate the time-dependent change in HrQoL.