Details

Autor(en) / Beteiligte

• Chhabra, Sachin
• Kunimoto, Derek Y.
• Kazi, Lubna
• Regillo, Carl D.
• Ho, Allen C.
• Belmont, Jonathan
• Maguire, Joseph
• Vander, James
• Brown, Gary C.

Titel

Endophthalmitis After Open Globe Injury: Microbiologic Spectrum and Susceptibilities of Isolates

Ist Teil von

• American journal of ophthalmology, 2006-11, Vol.142 (5), p.852-854

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

2006

Quelle

MEDLINE

Beschreibungen/Notizen

• To present the microbiologic spectrum and susceptibilities of isolates in posttraumatic endophthalmitis, and to provide a review of the literature. Retrospective consecutive case series. A review of 1182 consecutive open globe injuries was performed, identifying 10 patients with culture-proven endophthalmitis. Thirteen organisms were isolated from 10 eyes with posttraumatic endophthalmitis. Isolated organisms included Streptococcus species (46.2%), coagulase-negative Staphylococcus (23.1%), and Bacillus cereus (15.4%). All organisms tested were susceptible to vancomycin and tobramycin. The most commonly isolated organisms from an aggregate posttraumatic endophthalmitis pool of 372 cases obtained by literature-based meta-analysis were coagulase-negative Staphylococcus (21.5%) and Bacillus cereus (18.5%). We report a high prevalence of gram-positive pathogens and a notable prevalence of Bacillus cereus in posttraumatic endophthalmitis. Susceptibility results suggest that posttraumatic endophthalmitis isolates are generally susceptible to vancomycin and tobramycin.