Science (American Association for the Advancement of Science), 2005-11, Vol.310 (5752), p.1325-1326
2005
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Details
- Autor(en) / Beteiligte
- Titel
- Vertebrate-Type Intron-Rich Genes in the Marine Annelid Platynereis dumerilii
- Ist Teil von
- Science (American Association for the Advancement of Science), 2005-11, Vol.310 (5752), p.1325-1326
- Ort / Verlag
- Washington, DC: American Association for the Advancement of Science
- Erscheinungsjahr
- 2005
- Quelle
- American Association for the Advancement of Science
- Beschreibungen/Notizen
- Previous genome comparisons have suggested that one important trend in vertebrate evolution has been a sharp rise in intron abundance. By using genomic data and expressed sequence tags from the marine annelid Platynereis dumerilii, we provide direct evidence that about two-thirds of human introns predate the bilaterian radiation but were lost from insect and nematode genomes to a large extent. A comparison of coding exon sequences confirms the ancestral nature of Platynereis and human genes. Thus, the urbilaterian ancestor had complex, intron-rich genes that have been retained in Platynereis and human.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0036-8075eISSN: 1095-9203DOI: 10.1126/science.1119089Titel-ID: cdi_proquest_miscellaneous_68833289
- Format
- –
- Schlagworte
- Analysis, Animals, Annelida, Annelids, Bees, Bees - chemistry, Bees - genetics, Bilateria, Bilaterians, Biological and medical sciences, Biological evolution, Caenorhabditis elegans - chemistry, Caenorhabditis elegans - genetics, Ciona intestinalis - chemistry, Ciona intestinalis - genetics, Coding, Comparative analysis, Computational Biology, Datasets, Drosophila, Evolution, Evolution, Molecular, Exons, Fundamental and applied biological sciences. Psychology, Genes, Genetics of eukaryotes. Biological and molecular evolution, Genome, Genomes, Genomics, Humans, Introns, Marine, Molecular Sequence Data, Nematoda, Nematodes, Phylogeny, Platynereis, Platynereis dumerilii, Polychaeta - chemistry, Polychaeta - genetics, Proteins - chemistry, Proteins - genetics, Sequence Alignment, Species Specificity, Symmetry (Biology), Transcripts (Written Records), Vertebrates, Vertebrates - genetics