UNIVERSI
TÄ
TS-
BIBLIOTHEK
P
ADERBORN
Anmelden
Menü
Menü
Start
Hilfe
Blog
Weitere Dienste
Neuerwerbungslisten
Fachsystematik Bücher
Erwerbungsvorschlag
Bestellung aus dem Magazin
Fernleihe
Einstellungen
Sprache
Deutsch
Deutsch
Englisch
Farbschema
Hell
Dunkel
Automatisch
Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist
gegebenenfalls
nur via VPN oder Shibboleth (DFN-AAI) möglich.
mehr Informationen...
Universitätsbibliothek
Katalog
Suche
Details
Zur Ergebnisliste
Ergebnis 10 von 25
Datensatz exportieren als...
BibTeX
Preoperative lymph node staging of early‐stage cervical carcinoma by [18F]‐fluoro‐2‐deoxy‐D‐glucose–positron emission tomography
Cancer, 2005-12, Vol.104 (11), p.2484-2491
Wright, Jason D.
Dehdashti, Farrokh
Herzog, Thomas J.
Mutch, David G.
Huettner, Phyllis C.
Rader, Janet S.
Gibb, Randall K.
Powell, Matthew A.
Gao, Feng
Siegel, Barry A.
Grigsby, Perry W.
2005
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Wright, Jason D.
Dehdashti, Farrokh
Herzog, Thomas J.
Mutch, David G.
Huettner, Phyllis C.
Rader, Janet S.
Gibb, Randall K.
Powell, Matthew A.
Gao, Feng
Siegel, Barry A.
Grigsby, Perry W.
Titel
Preoperative lymph node staging of early‐stage cervical carcinoma by [18F]‐fluoro‐2‐deoxy‐D‐glucose–positron emission tomography
Ist Teil von
Cancer, 2005-12, Vol.104 (11), p.2484-2491
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2005
Quelle
Wiley Online Library All Journals
Beschreibungen/Notizen
BACKGROUND Increasing evidence has documented the value of positron emission tomography (PET) in oncology, but only limited data are available comparing PET findings with the pathologic status of regional lymph nodes in patients with cervical carcinoma. The objective of this study was to determine the sensitivity and specificity of PET in detecting lymph node metastasis in women with early‐stage cervical carcinoma. METHODS The authors performed a retrospective review of all patients with Stage IA–IIA cervical carcinoma who underwent PET before surgery from 1999 to 2004. The status of the regional lymph nodes was correlated with lymph node pathology. RESULTS Fifty‐nine patients were identified. Pelvic lymph node metastases were present in 32% of the patients and were detected by PET with a sensitivity of 53%, a specificity of 90%, a positive predictive value (PPV) of 71%, and a negative predictive value (NPV) of 80%. Paraaortic lymph node disease was present in 9% of patients and was detected by PET with a sensitivity of 25%, a specificity 98%, a PPV of 50%, and an NPV of 93%. The mean size of the tumor deposits was larger in the PET‐positive pelvic nodes (15.2 mm; range, 2–35 mm) than in the PET‐negative lymph nodes (7.3 mm; range, 0.3–20 mm; P = 0.002). Computed tomography (CT) scans were obtained before surgery in 42 patients. The combined sensitivity of PET and CT in these patients was 75%. PET alone detected 9 (36%) of the positive lymph node groups, whereas CT alone detected 3 (12%) of the positive lymph node groups. Neither PET nor CT detected the positive lymph node groups in 8 patients (32%). CONCLUSIONS Pathologic validation of PET imaging demonstrated a low sensitivity and a high specificity for PET in patients with early‐stage cervical carcinoma. Cancer 2005. © 2005 American Cancer Society. Preoperative [18F]‐fluoro‐2‐deoxy‐D‐glucose–positron emission tomography imaging for women with early‐stage cervical carcinoma demonstrated a low sensitivity and a high specificity for the detection of lymph node metastases.
Sprache
Englisch
Identifikatoren
ISSN: 0008-543X
eISSN: 1097-0142
DOI: 10.1002/cncr.21527
Titel-ID: cdi_proquest_miscellaneous_68828214
Format
–
Schlagworte
[18F]‐fluoro‐2‐deoxy‐D‐glucose‐positron emission tomography
,
Biological and medical sciences
,
cervical carcinoma
,
Female
,
Female genital diseases
,
Fluorodeoxyglucose F18
,
Gynecology. Andrology. Obstetrics
,
Humans
,
Hysterectomy
,
Lymph Nodes - diagnostic imaging
,
Lymph Nodes - pathology
,
lymphadenectomy
,
Medical sciences
,
Neoadjuvant Therapy
,
Neoplasm Invasiveness
,
Neoplasm Metastasis
,
Neoplasm Staging
,
Positron-Emission Tomography - methods
,
radical hysterectomy
,
Radiopharmaceuticals
,
Retrospective Studies
,
Tumors
,
Uterine Cervical Neoplasms - diagnostic imaging
,
Uterine Cervical Neoplasms - pathology
,
Uterine Cervical Neoplasms - surgery
,
Vaginal Neoplasms - pathology
,
Vaginal Neoplasms - secondary
Weiterführende Literatur
Empfehlungen zum selben Thema automatisch vorgeschlagen von
bX