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Absence of ductus venosus—importance of umbilical venous drainage site
Ultrasound in obstetrics & gynecology, 2006-09, Vol.28 (3), p.275-281
Berg, C.
Kamil, D.
Geipel, A.
Kohl, T.
Knöpfle, G.
Hansmann, M.
Gembruch, U.
2006
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Berg, C.
Kamil, D.
Geipel, A.
Kohl, T.
Knöpfle, G.
Hansmann, M.
Gembruch, U.
Titel
Absence of ductus venosus—importance of umbilical venous drainage site
Ist Teil von
Ultrasound in obstetrics & gynecology, 2006-09, Vol.28 (3), p.275-281
Ort / Verlag
Chichester, UK: John Wiley & Sons, Ltd
Erscheinungsjahr
2006
Quelle
Wiley-Blackwell Journals
Beschreibungen/Notizen
Objective To evaluate the conditions associated with absent ductus venosus (ADV) diagnosed by prenatal ultrasonography. Methods Retrospective review of 23 cases with ADV diagnosed in two tertiary referral centers with a general screening policy concerning Doppler assessment of the ductus venosus. The results are discussed together with 63 cases from a review of the literature. Results In 19 fetuses the umbilical vein connected to the portal sinus, while the remaining four fetuses had extrahepatic umbilical venous drainage. Associated anomalies were present in 15 out of 23 fetuses: complex malformation syndromes (n = 6), chromosomal anomalies (n = 4), isolated cardiac defects (n = 4) and isolated extracardiac anomalies (n = 1). Eight fetuses had either no associated anomalies or minor anomalies. Hydropic changes were present in 12 of the 23 fetuses. In common with the reviewed cases, the presence of cardiac malformations, complex non‐chromosomal malformation syndromes and hydrops was significantly associated with intrauterine or postnatal death while the type of umbilical venous drainage was not significantly different between survivors and non‐survivors. However, among fetuses with no or minor associated anomalies the outcome was significantly better in the group without liver bypass. Conclusions ADV is significantly associated with fetal cardiac and extracardiac anomalies, aneuploidies and hydrops. Fetuses with liver bypass have an additional risk of developing congestive heart failure that significantly affects outcome, even if the fetal cardiovascular anatomy is otherwise normal. ADV without liver bypass seems to have a more favorable prognosis if it is not associated with other malformations. Copyright © 2006 ISUOG. Published by John Wiley & Sons, Ltd.
Sprache
Englisch
Identifikatoren
ISSN: 0960-7692
eISSN: 1469-0705
DOI: 10.1002/uog.2811
Titel-ID: cdi_proquest_miscellaneous_68804522
Format
–
Schlagworte
Aneuploidy
,
Biological and medical sciences
,
Diseases of mother, fetus and pregnancy
,
Doppler
,
ductus venosus agenesis
,
Edema - diagnostic imaging
,
Female
,
Fetal Diseases - diagnostic imaging
,
Fetal Heart - abnormalities
,
fetus
,
Fetus - blood supply
,
Gynecology. Andrology. Obstetrics
,
Heart Failure - congenital
,
Humans
,
hydrops
,
Medical sciences
,
Pregnancy
,
Pregnancy. Fetus. Placenta
,
prenatal diagnosis
,
Retrospective Studies
,
sonography
,
Ultrasonography, Prenatal
,
Umbilical Veins - abnormalities
,
Umbilical Veins - diagnostic imaging
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