Phytomedicine (Stuttgart), 2005-09, Vol.12 (9), p.670-674
2005
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- Autor(en) / Beteiligte
- Titel
- A study of the antidiarrheal properties of Loeselia mexicana on mice and rats
- Ist Teil von
- Phytomedicine (Stuttgart), 2005-09, Vol.12 (9), p.670-674
- Ort / Verlag
- Germany: Elsevier GmbH
- Erscheinungsjahr
- 2005
- Quelle
- Elsevier ScienceDirect Journals
- Beschreibungen/Notizen
- Antidiarrheal properties of hexane, chloroform, methanol and aqueous extracts from Loeselia mexicana were studied using mice and rats as animal models. Flavones and sesquiterpenlactones were detected in the chemical screening of the aqueous extract. Diarrhea was induced by castor oil or MgSO 4. The methanol extract diminished diarrhea in mice induced by MgSO 4, while the aqueous extract showed an effect on castor-oil-induced. The aqueous extract also reduced castor-oil-enhanced intestinal transit and inhibited defecation of normal mice. The results obtained showed a symptomatic relief of diarrhea.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0944-7113eISSN: 1618-095XDOI: 10.1016/j.phymed.2004.01.010Titel-ID: cdi_proquest_miscellaneous_68639814
- Format
- –
- Schlagworte
- Administration, Oral, Animals, Antidiarrheal effect, Antidiarrheals - administration & dosage, Antidiarrheals - pharmacology, Antidiarrheals - therapeutic use, Biologically active extracts, Care and treatment, defecation, Diarrhea, Disease Models, Animal, essential oils, Gastrointestinal Motility - drug effects, gastrointestinal transit, Loeselia mexicana, Magnoliopsida, Male, medicinal plants, Mice, Mice, Inbred Strains, Phytotherapy, plant extracts, Plant Extracts - administration & dosage, Plant Extracts - pharmacology, Plant Extracts - therapeutic use, Plant Leaves, Plant Oils - administration & dosage, Plant Oils - pharmacology, Plant Oils - therapeutic use, Polemoniaceae, Rats, Rats, Wistar