Details

Autor(en) / Beteiligte

• Stanisz, Greg J.
• Odrobina, Ewa E.
• Pun, Joseph
• Escaravage, Michael
• Graham, Simon J.
• Bronskill, Michael J.
• Henkelman, R. Mark

Titel

T1, T2 relaxation and magnetization transfer in tissue at 3T

Ist Teil von

• Magnetic resonance in medicine, 2005-09, Vol.54 (3), p.507-512

Ort / Verlag

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

Erscheinungsjahr

2005

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• T1, T2, and magnetization transfer (MT) measurements were performed in vitro at 3 T and 37°C on a variety of tissues: mouse liver, muscle, and heart; rat spinal cord and kidney; bovine optic nerve, cartilage, and white and gray matter; and human blood. The MR parameters were compared to those at 1.5 T. As expected, the T2 relaxation time constants and quantitative MT parameters (MT exchange rate, R, macromolecular pool fraction, M0B, and macromolecular T2 relaxation time, T2B) at 3 T were similar to those at 1.5 T. The T1 relaxation time values, however, for all measured tissues increased significantly with field strength. Consequently, the phenomenological MT parameter, magnetization transfer ratio, MTR, was lower by approximately 2 to 10%. Collectively, these results provide a useful reference for optimization of pulse sequence parameters for MRI at 3 T. Magn Reson Med, 2005. © 2005 Wiley‐Liss, Inc.