Details

Autor(en) / Beteiligte

• Albermann, Kaj
• Lang, Stephan
• Zeidler, Reinhard

Titel

Molecular Profiling for the Identification of New Biomarkers in Smokers and Cancer Patients

Ist Teil von

• Cancer genomics & proteomics, 2007-09, Vol.4 (5), p.349-358

Ort / Verlag

Greece: International Institute of Anticancer Research

Erscheinungsjahr

2007

Quelle

MEDLINE

Beschreibungen/Notizen

• Smoking is associated with different serious diseases, including cancer. The fact that only a minority of smokers develops tobacco-associated diseases suggests the contribution of other individual factors, which are still far from understood. New technologies that can be referred to as ‘molecular profiling’ allow for investigating the deregulation of thousands of genes simultaneously. Numerous such studies have investigated in vitro and in vivo the effects of smoking in different cell types aiming at a better understanding of smoking-induced diseases and the detection of new biomarkers of exposure and harm. This review is a short survey of these investigations and how they have contributed to the detection of new biomarkers and to a better understanding of smoking-induced harm.