AIDS (London), 2007-01, Vol.21 (1), p.103-106
2007
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- Autor(en) / Beteiligte
- Titel
- Virological characterization of an infection with a dual-tropic, multidrug-resistant HIV-1 and further evolution on antiretroviral therapy
- Ist Teil von
- AIDS (London), 2007-01, Vol.21 (1), p.103-106
- Ort / Verlag
- Hagerstown, MD: Lippincott Williams & Wilkins
- Erscheinungsjahr
- 2007
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- We studied a case of recent infection with multidrug-resistant (MDR) HIV-1. Over 16 months off-therapy, the CD4 cell count decreased from 419 to 184 cells/mul. Antiretroviral therapy (ART) then led to an incomplete virological response but to an immunological benefit, concurrently with a shift to CCR5-only tropism and a reduction in replication capacity. ART, even if suboptimal, can be of interest in the case of MDR virus infection.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0269-9370eISSN: 1473-5571DOI: 10.1097/QAD.0b013e3280117053Titel-ID: cdi_proquest_miscellaneous_68368546
- Format
- –
- Schlagworte
- Adult, AIDS/HIV, Anti-Retroviral Agents - therapeutic use, Antibiotics. Antiinfectious agents. Antiparasitic agents, Antiviral agents, Biological and medical sciences, CD4 Lymphocyte Count, Drug Resistance, Multiple, Viral, Genotype, HIV Infections - drug therapy, HIV Infections - immunology, HIV Infections - virology, HIV-1 - genetics, Human viral diseases, Humans, Immunodeficiencies, Immunodeficiencies. Immunoglobulinopathies, Immunopathology, Infectious diseases, Male, Medical sciences, Pharmacology. Drug treatments, Receptors, CCR5 - metabolism, Viral diseases, Viral diseases of the lymphoid tissue and the blood. Aids, Viral Load