Details

Autor(en) / Beteiligte

• Puthanakit, Thanyawee
• Aurpibul, Linda
• Oberdorfer, Peninnah
• Akarathum, Noppadon
• Kanjanavanit, Suparat
• Wannarit, Pornphun
• Sirisanthana, Thira
• Sirisanthana, Virat

Titel

Sustained immunologic and virologic efficacy after four years of highly active antiretroviral therapy in human immunodeficiency virus infected children in Thailand

Ist Teil von

• The Pediatric infectious disease journal, 2007-10, Vol.26 (10), p.953

Ort / Verlag

United States

Erscheinungsjahr

2007

Quelle

MEDLINE

Beschreibungen/Notizen

• We report the long-term efficacy of highly active antiretroviral therapy (HAART) in 107 antiretroviral-naive human immunodeficiency virus (HIV)-infected Thai children. In an intention-to-treat analysis, 70% of the children had undetectable HIV RNA titers after 192 weeks of HAART. The mean CD4 cell percentage increased from 5.3% to 26.6%. HAART is effective for HIV-infected children in this resource-poor setting despite initiation of treatment in the advanced stage of disease.