Small (Weinheim an der Bergstrasse, Germany), 2006-02, Vol.2 (2), p.254-256
2006
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Details
- Autor(en) / Beteiligte
- Titel
- Ordered Mesoporous Silica SBA‐15: A New Effective Adjuvant to Induce Antibody Response
- Ist Teil von
- Small (Weinheim an der Bergstrasse, Germany), 2006-02, Vol.2 (2), p.254-256
- Ort / Verlag
- Weinheim: WILEY‐VCH Verlag
- Erscheinungsjahr
- 2006
- Quelle
- Wiley Online Library Journals Frontfile Complete
- Beschreibungen/Notizen
- Adding to antibodies: Ordered mesoporous silicas such as SBA‐15 may be used as adjuvants to carry, protect, and deliver entrapped antigens, thereby assuring efficient stimulation of antigen‐presenting cells and improving antibody responsiveness. Thus, SBA‐15 and related silica mesostructures seem to be promising nanosystems for vaccine delivery. Venom proteins from the Micrurus ibiboboca snake (see picture) were utilized in the study.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1613-6810eISSN: 1613-6829DOI: 10.1002/smll.200500274Titel-ID: cdi_proquest_miscellaneous_68271462
- Format
- –
- Schlagworte
- adjuvant effect, Adjuvants, Immunologic - analysis, antibodies, Antigen-Antibody Complex - analysis, Biocompatible Materials - chemistry, Immunoassay - methods, Materials Testing, mesoporous materials, Nanostructures - chemistry, Nanostructures - ultrastructure, Nanotechnology - methods, Porosity, proteins, silica, Silicon Dioxide - chemistry, Snake Venoms - chemistry, Snake Venoms - immunology