Details

Autor(en) / Beteiligte

• Ogawa, Masahiro, MD, PhD
• Zhou, Shengmei, MD
• Tan, Alex Y., MD
• Song, Juan, PhD
• Gholmieh, Ghassan, MD, PhD
• Fishbein, Michael C., MD, FACC
• Luo, Huai, MD
• Siegel, Robert J., MD, FACC
• Karagueuzian, Hrayr S., PhD
• Chen, Lan S., MD
• Lin, Shien-Fong, PhD
• Chen, Peng-Sheng, MD, FACC

Titel

Left Stellate Ganglion and Vagal Nerve Activity and Cardiac Arrhythmias in Ambulatory Dogs With Pacing-Induced Congestive Heart Failure

Ist Teil von

• Journal of the American College of Cardiology, 2007-07, Vol.50 (4), p.335-343

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

2007

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Left Stellate Ganglion and Vagal Nerve Activity and Cardiac Arrhythmias in Ambulatory Dogs With Pacing-Induced Congestive Heart Failure Masahiro Ogawa, Shengmei Zhou, Alex Y. Tan, Juan Song, Ghassan Gholmieh, Michael C. Fishbein, Huai Luo, Robert J. Siegel, Hrayr S. Karagueuzian, Lan S. Chen, Shien-Fong Lin, Peng-Sheng Chen We implanted radiotransmitters in 6 dogs for continuous autonomic nerve recording before and after pacing-induced congestive heart failure (CHF). Most prolonged sinus pause episodes occurred at night and were preceded by a short burst of stellate ganglion nerve activity (SGNA). Long (>10 s) paroxysmal atrial tachycardia (PAT) episodes were typically (83%) induced by simultaneous SGNA and vagal nerve activity (VNA) discharge, followed by VNA withdrawal. We conclude that the tachybrady syndrome in CHF might be due to intermittent short burst of SGNA. Simultaneous sympathovagal discharge is a cause of long PAT episodes. There is an association between the specific patterns of autonomic nerve discharges and cardiac arrhythmia during CHF.