Details

Autor(en) / Beteiligte

• Nagase, Satoshi, MD
• Kusano, Kengo Fukushima, MD
• Morita, Hiroshi, MD
• Nishii, Nobuhiro, MD
• Banba, Kimikazu, MD
• Watanabe, Atsuyuki, MD
• Hiramatsu, Shigeki, MD
• Nakamura, Kazufumi, MD
• Sakuragi, Satoru, MD
• Ohe, Tohru, MD

Titel

Longer Repolarization in the Epicardium at the Right Ventricular Outflow Tract Causes Type 1 Electrocardiogram in Patients With Brugada Syndrome

Ist Teil von

• Journal of the American College of Cardiology, 2008-03, Vol.51 (12), p.1154-1161

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2008

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Longer Repolarization in the Epicardium at the Right Ventricular Outflow Tract Causes Type 1 Electrocardiogram in Patients With Brugada Syndrome Satoshi Nagase, Kengo Fukushima Kusano, Hiroshi Morita, Nobuhiro Nishii, Kimikazu Banba, Atsuyuki Watanabe, Shigeki Hiramatsu, Kazufumi Nakamura, Satoru Sakuragi, Tohru Ohe We recorded epicardial and endocardial electrograms at the right ventricular outflow tract directly in 19 patients with Brugada syndrome and 3 control subjects, and we examined the relationship between repolarization abnormality and coved-type ST-segment elevation with terminal inverted T-wave (type 1 electrocardiogram [ECG]). Surface ECG, activation-recovery intervals, and repolarization times were examined before and after administration of pilsicainide. We found that activation-recovery intervals and repolarization time recordings provide support for the hypothesis that the negative T-wave associated with type 1 ECG is due to a preferential prolongation of the epicardial action potential at the right ventricular outflow tract.