Reproduction (Cambridge, England), 2005-08, Vol.130 (2), p.131-145
2005
Details
- Autor(en) / Beteiligte
- Titel
- Leukaemia inhibitory factor in implantation and uterine biology
- Ist Teil von
- Reproduction (Cambridge, England), 2005-08, Vol.130 (2), p.131-145
- Ort / Verlag
- Colchester: Society for Reproduction and Fertility
- Erscheinungsjahr
- 2005
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Leukaemia inhibitory factor (LIF) is one of the most important cytokines in the reproductive tract. Without expression of LIF in the uterus, implantation of a blastocyst cannot begin. Yet, 13 years after publication of the phenotype of the LIF knockout mouse we are only just beginning to understand how LIF functions in the uterus. This review addresses our knowledge of the role of LIF in regulating implantation through its influence on the luminal epithelium and stromal decidualization, but also its influence on reproductive tract cells such as leukocytes and glandular epithelium, during the pre-implantation phase of pregnancy.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1470-1626eISSN: 1741-7899DOI: 10.1530/rep.1.00304Titel-ID: cdi_proquest_miscellaneous_68083251
- Format
- –
- Schlagworte
- Animals, Biological and medical sciences, cytokines, Decidua - physiology, embryo implantation, Embryo Implantation - physiology, Embryonic Development - physiology, epithelium, Epithelium - physiology, Female, Fundamental and applied biological sciences. Psychology, Gene Expression Regulation, Developmental, Humans, Interleukin-6 - genetics, Interleukin-6 - physiology, leukemia, Leukemia Inhibitory Factor, leukocytes, Leukocytes - physiology, Mammalian female genital system, Mice, Mice, Knockout, Morphology. Physiology, phenotype, Pregnancy, Pregnancy, Animal - physiology, REVIEW, uterus, Uterus - physiology, Vertebrates: reproduction