Journal of natural products (Washington, D.C.), 2005-07, Vol.68 (7), p.1006-1009
2005
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Details
- Autor(en) / Beteiligte
- Titel
- Bioactive Constituents of the Leaves of Phyllanthus polyphyllus var. siamensis
- Ist Teil von
- Journal of natural products (Washington, D.C.), 2005-07, Vol.68 (7), p.1006-1009
- Ort / Verlag
- Washington, DC: American Chemical Society
- Erscheinungsjahr
- 2005
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- A dichloromethane extract of the leaves of Phyllanthus polyphyllus var. siamensis afforded two new monoacetylated triterpene arabinosides (1 and 2) and 15 known compounds. The structures of the new compounds were elucidated on the basis of spectroscopic data interpretation. The isolates and some chemical transformation products were evaluated biologically, and the presence of an arabinosyl moiety among the hederagenin glycosides evaluated was found to be important for the modulation of cytotoxic activity against cancer cells.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0163-3864eISSN: 1520-6025DOI: 10.1021/np050001aTitel-ID: cdi_proquest_miscellaneous_68075023
- Format
- –
- Schlagworte
- anticarcinogenic activity, Antineoplastic Agents, Phytogenic - chemistry, Antineoplastic Agents, Phytogenic - isolation & purification, Antineoplastic Agents, Phytogenic - pharmacology, arabinose, Biological and medical sciences, chemical structure, cultured cells, cytotoxicity, Drug Screening Assays, Antitumor, General pharmacology, glycosides, human health, humans, Medical sciences, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Oleanolic Acid - analogs & derivatives, Oleanolic Acid - chemistry, Oleanolic Acid - isolation & purification, Oleanolic Acid - pharmacology, Pharmacognosy. Homeopathy. Health food, Pharmacology. Drug treatments, Phyllanthus, Phyllanthus - chemistry, Phyllanthus polyphyllus var. siamensis, phytochemicals, plant extracts, Plant Leaves - chemistry, Plants, Medicinal - chemistry, spectral analysis, Thailand, triterpenoids, Tumor Cells, Cultured