Trends in genetics, 2005-08, Vol.21 (8), p.436-440
2005
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- Autor(en) / Beteiligte
- Titel
- Striking nucleotide frequency pattern at the borders of highly conserved vertebrate non-coding sequences
- Ist Teil von
- Trends in genetics, 2005-08, Vol.21 (8), p.436-440
- Ort / Verlag
- Oxford: Elsevier Ltd
- Erscheinungsjahr
- 2005
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- In a recent study, 1373 highly conserved non-coding elements (CNEs) were detected by aligning the human and Takifugu rubripes (Fugu) genomes. The remarkable degree of sequence conservation in CNEs compared with their surroundings suggested comparing the base composition within CNEs with their 5′ and 3′ flanking regions. The analysis reveals a novel, sharp and distinct signal of nucleotide frequency bias precisely at the border between CNEs and flanking regions.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0168-9525DOI: 10.1016/j.tig.2005.06.003Titel-ID: cdi_proquest_miscellaneous_68055525
- Format
- –
- Schlagworte
- Animals, Base Composition, Biological and medical sciences, Conserved Sequence, DNA - chemistry, DNA - genetics, Fundamental and applied biological sciences. Psychology, Genetics of eukaryotes. Biological and molecular evolution, Humans, Molecular and cellular biology, Takifugu - genetics, Vertebrates - genetics