Pediatric transplantation, 2006-06, Vol.10 (4), p.501-504
2006
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Successful unrelated mismatched cord blood transplantation in an infant with severe combined immunodeficiency and Mycobacterium bovis bacillus Calmette‐Guèrin disease
- Ist Teil von
- Pediatric transplantation, 2006-06, Vol.10 (4), p.501-504
- Ort / Verlag
- Oxford, UK: Blackwell Publishing Ltd
- Erscheinungsjahr
- 2006
- Quelle
- Wiley-Blackwell Journals
- Beschreibungen/Notizen
- : The case reported here of an infant who presented with Pneumocystis carinii pneumonia, CD4+ lymphopenia, and hypogammaglobulinemia attributable to severe combined immunodeficiency (SCID). This report discussed treatment of Mycobacterium bovis bacillus Calmette‐Guèrin disease with unrelated cord blood transplantation in addition to antituberculous therapy, by adoptively transferring donor immunity with induction of mixed chimerism. Because of the unique nature of umbilical cord blood hematopoietic cells, engraftment without conditioning may be possible in SCID patients without fully matched donors.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1397-3142eISSN: 1399-3046DOI: 10.1111/j.1399-3046.2006.00490.xTitel-ID: cdi_proquest_miscellaneous_67997280
- Format
- –
- Schlagworte
- bacillus Calmette‐Guèrin, Biological and medical sciences, Cord Blood Stem Cell Transplantation, Follow-Up Studies, Histocompatibility, Histocompatibility Testing, Humans, Infant, Male, Medical sciences, Mycobacterium bovis, Pneumocystis carinii, severe combined immunodeficiency, Severe Combined Immunodeficiency - immunology, Severe Combined Immunodeficiency - therapy, Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases, Time Factors, Treatment Outcome, Tuberculosis - microbiology, unrelated mismatched cord blood transplantation